Table 2 Demographic data for arm B of SANAD
From: Guide to evaluating performance of prediction models for recurrent clinical events
Variable | Valproate (n = 234) | Lamotrigine (n = 235) | Topiramate (n = 233) | Total (n = 702) | |
|---|---|---|---|---|---|
Gender | Female | 93 (40) | 95 (40) | 93 (40) | 281 (40) |
Male | 141 (60) | 140 (60) | 141 (60) | 422 (60) | |
Primary relative with epilepsy | Absent | 197 (84) | 183 (78) | 195 (84) | 575 (82) |
Present | 37 (16) | 52 (22) | 38 (16) | 127 (18) | |
Age at randomisation (years), median (IQR) [range] | 18.9 (12.5, 27.6) [5.0, 76.9] | 18.6 (12.8, 29.1) [5.3, 77.1] | 18.9 (12.5, 27.6) [5.0, 75.2] | 18.9 (12.5, 28.3) [5.0, 77.1] | |
No seizures during follow-up | 82 (35) | 58 (25) | 72 (31) | 212 (30) | |
Tonic–clonic seizures | Annual seizure rate prior to randomisation % < 1 seizure/year | 60.8 | 51.5 | 31.8 | 48.0 |
Median (IQR) for those with rate ≥ 1 seizure/yr | 53 16.7 (4.4, 50.5) | 35 21.5 (4.0, 63.7) | 44 16.3 (3.5, 68.4) | 44 17.95 (3.9, 63.2) | |