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Table 1 PICOTS format used for eligibility assessment

From: Clinical prognostic models for sarcomas: a systematic review and critical appraisal of development and validation studies

PICOTS framework

Eligibility criteria for this systematic review

P—Participants

Patients with a histological diagnosis of soft tissue or bone sarcoma

I—Index models

All clinical prognostic models predict overall survival, event-free survival, progression-free survival, disease-specific survival/sarcoma-specific survival, progression of disease, local recurrence rate, systemic recurrence rate and development of metastasis

C—Comparator

Not applicable because we aim to identify all models that were developed and/or validated for sarcomas

O—Outcome

Overall survival, event-free survival, progression-free survival, disease-specific survival/sarcoma-specific survival, progression of the disease, local recurrence rate, systemic recurrence rate and development of metastasis

T—Timing

Any timing starting with the date of pathologically established diagnosis

S—Setting

Any setting